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Chapter-03 Epicardial Reperfusion

BOOK TITLE: Textbook of Cardiology (A Clinical & Historical Perspective)

Author
1. Chopra HK
2. Sambi RS
3. Krishna CK
ISBN
9789350900819
DOI
10.5005/jp/books/12259_3
Edition
1/e
Publishing Year
2013
Pages
5
Author Affiliations
1. Moolchand Medcity Hospital, New Delhi, India, Medanta Moolchand Heart Institute, Moolchand Medcity, New Delhi, India, Medanta Moolchand Heart Institute, Moolchand Medcity; World Wellness Foundation, WHA; AHA, Medanta Moolchand Heart Institute; Moolchand Medcity; World Wellness Foundation, WHA; CSI & IAE; IHJ, JIAE, Medanta Moolchand Heart Institute; Moolchand Medcity; World Wellness Foundation, WHA, Medanta Moolchand Heart Institute, New Delhi, India; CME, Moolchand Medcity, World Wellness, Foundation and WHA; AHA; CSI and IAE; IHJ and JIAE, IAE-2017, CSI-2015; World Wellness Foundation, Country Head, American Heart Association; Medanta Moolchand Heart Institute; Health Committee, SCOPE, Tata Sky FAM Health, New Delhi, India, IAE- 2017, CSI -2015; World Wellness Foundation; American Heart Association; Moolchand Medcity; Physician Governing Body, CME, COP Moolchand Medcity, New Delhi, India, IAE- 2017, CSI -2015; World Wellness Foundation; Physician Governing Body, CME, COP Moolchand Medcity, New Delhi, India
2. National Heart Institute, New Delhi, India
3. Moolchand Medcity, New Delhi, India
Chapter keywords
epicardial reperfusion, thrombosed epicardial blood vessels, coronary atherosclerosis, myocardial infarction, luminal thrombus, ischemia, myocardial contractility

Abstract

Restoration of blood flow in the thrombosed epicardial blood vessels is termed as epicardial reperfusion. Coronary atherosclerosis is the major etiology for myocardial infarction (MI), with more than 90% cases associated with superimposed luminal thrombus on a ruptured plaque. The biochemical and functional abnormalities begin almost immediately at the onset of ischemia and severe loss of myocardial contractility occurs within 60 seconds. The “no-reflow” phenomenon can be defined as an acute and severe reduction in coronary flow after removal of an arterial occlusion, in the absence of spasm, thrombi, severe residual lesions and arterial dissection. Measures of epicardial reperfusion are explained. Reperfusion strategies are described.

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