There are many factors that may influence aneurysm formation. Some of the significant factors include genetics, mechanical and material properties of the vascular wall, and the hemodynamic environment within the cerebral vasculature. Among these the hemodynamics plays an important role during aneurysm formation and development. The aneurysmal rupture occurs when the aneurysmal wall can no longer withstand the hemodynamic forces within the aneurysm. There are three major hemodynamic risk factors such as low wall shear stress (WSS) that weakens the structural properties of the aneurysmal wall, high WSS that leads to destructive remodeling of the aneurysmal wall, and high pressure on the aneurysmal wall. The in vivo, in vitro, and computational techniques are used for evaluating and measuring aneurysm hemodynamics. The chapter also discusses about the factors that influence cerebral aneurysm hemodynamics, and endovascular treatment of cerebral aneurysms.