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Chapter-057 Anterior Corneal Dystrophies: Dystrophies of the Epithelium, Epithelial Basement Membrane and Bowman's Layer

BOOK TITLE: Copeland and Afshari's Principles and Practice of Cornea (2 Volumes)

Author
1. Sherman Mark D
ISBN
9789350901724
DOI
10.5005/jp/books/11777_57
Edition
1/e
Publishing Year
2013
Pages
10
Author Affiliations
1. Pacific Eye Surgeons, San Luis Obispo, California; Loma Linda University School of Medicine, Loma Linda, California, USA, Loma Linda University School of Medicine, Loma Linda, California, USA
Chapter keywords
Anterior corneal dystrophy, epithelial basement membrane dystrophy, epithelial recurrent erosion dystrophy, subepithelial mucinous corneal dystrophy, Meesmann corneal dystrophy, Lisch epithelial corneal dystrophy, gelatinous drop-like corneal dystrophy, Reis-Buckler’s corneal dystrophy, Thiel-Behnke corneal dystrophy, Grayson-Wilbrandt corneal dystrophy, Bowman’s layer

Abstract

In this chapter nine anterior corneal dystrophies have been discussed namely, epithelial basement membrane dystrophy (EBMD), epithelial recurrent erosion dystrophy (ERED), subepithelial mucinous corneal dystrophy (SMCD), Meesmann corneal dystrophy (MECD), Lisch epithelial corneal dystrophy (LECD), gelatinous drop-like corneal dystrophy (GDLD), Reis-Buckler’s corneal dystrophy (RBCD), Thiel-Behnke corneal dystrophy (TBCD) and Grayson-Wilbrandt corneal dystrophy (GWCD). EBMD is the most common anterior corneal dystrophy and the lesions may be unilateral, bilateral and bilaterally asymmetric. ERED presents with bilateral symptomatic corneal erosions. SMCD presents with recurrent bilateral corneal erosions progressing to vision loss. MECD is a bilaterally symmetric, autosomal dominant disorder. LECD presents with unilateral and bilateral gray granular opacities in a band-shaped pattern with whorled and feathery borders. GDLD is characterized by multiple coalescing gelatinous deposits just below the corneal epithelium. RBCD is a bilaterally symmetric which involves the central corneal axis. TBCD presents with central bilateral subepithelial reticular opacities. The GWCD causes loss of vision due to corneal surface irregularity.

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