First time syndactyly identified as birth anomaly,first physician to do a post-mortem dissection, earliest known example of conjoined twins,conjoined at the back (pygophagus) whos names are knownMary and Eliza Chulkhurst. Averroes study on photoreceptor property of retina and his suggestion that the principle sight organ might be the arachnoid membrane, Ibn al-Nafis first to describe pulmonary and coronary circulation, historical marriage between full siblings John V Count of armagnac and isabelle D’ armagnac in Germany. First medical book written in printed format based on Greek and Arab Works written by Paolo Bagellardo, First successful caesarean section with survival of both mother and baby, Situs invertus first discovered by Leonardo da Vinci