This chapter will first briefly recall the procedures clinicians could rely on for the diagnosis and evaluation of cardiac lesions before the Doppler gestation period, in the 1960s. Then the introduction of the cardiac Doppler era, slowly elaborated in several steps by a handful of pioneers in a few sites around the world, laid the foundation for the development from which we benefit today. The history of Doppler is a long series of small advances with multiple hesitant paths, some of them leading to deadlocks, and, suddenly, some exciting breakthroughs! Given these to-and-fro advances, writing the history of the early Doppler era cannot follow a strict chronology, but it rather follows the different streamlines of research, some interrupted like the nondirectional Doppler, some others coming back about 30 years later like tissue Doppler imaging through technological progresses, some finally gaining acceptance as directional flow Doppler, through accompanying improvements in imaging modalities and color coding. Continuous wave Doppler quantitative capabilities also representing a major streamline from the last half of the 1970s will reinforce the Doppler technique as a unique noninvasive tool accepted by cardiologists. In brief, the chapter will outline the successive changes in this flow Doppler era from the 1960s till the last decade before the new millennium. Thus, the first steps of pioneers in the desert land of cardiac Doppler, and on the explosive and fruitful research on flow dynamics which paved the way for their success and guided them during more than 30 years. 37 well-illustrated self-explanatory and comprehensive images are included in this chapter. 71 recent references have been added in this chapter useful tool for further reading.