Manual of Ovulation Induction & Ovarian Stimulation Protocols

by Gautam N Allahbadia, Rubina Merchant

The objective of this book is to introduce the manual of ovulation induction and ovarian stimulation protocols. This book divided into nine significant sections, with 67 carefully designed chapters, contributed by world authorities with clinical and scientific excellence, is a complete guide that aims to answer all these baffling questions and more in a single edition. The introductory section on the fundamentals of stimulation forms the scaffold, giving a thorough insight into the physiology of folliculogenesis and ovulation, regulation of gonadotropin secretion, their roles in follicular development and the menstrual cycle, and the effect of controlled ovarian hyperstimulation (COH) on cycle characteristics, indispensable to the understanding of cycle manipulation with ovulation indication (OI) drugs. The clinical significance of evaluating the ovarian reserve and monitoring folliculogenesis with ovarian reserve markers to predict the ovarian response to COH is detailed, with particular relevance to high and poor responders to COH—the two most challenging patient groups. The value of LH supplementation, evaluation of the luteal phase and the significance of luteal phase support in COH are addressed to optimize the pregnancy outcomes with COH. The section on ovarian stimulation regimens that follows comprehensively, discusses the gamut of ovarian stimulation drugs (CC, urinary and recombinant gonadotropins, GnRH agonists and antagonists, and the novel recombinant long-acting Corifollitropin-alfa), the various protocols in which they are used (long, short, ultrashort, microdose-flare GnRH protocols, step-up protocols, step-down protocols), their clinical applications, comparative clinical efficacies, routes of administration and clinical outcomes, endowing the clinicians with the ability to appropriately individualize the treatment to patients.

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Book Detail

Editor
1. Allahbadia Gautam N
2. Merchant Rubina
Editor's Affiliation
1. The Prince Aly Khan Hospital IVF Center and The Aesculap Academy-Asia, Pacific Center for Minimally Invasive Surgery, Training and Research, Mazgaon, Mumbai, India
2. Rotunda - The Center for Human Reproduction, Bandra, Mumbai, India
ISBN
9789350909584
Speciality
Obstetrics and Gynecology
DOI
10.5005/jp/books/12832
Edition
3/e
Publishing Year
2016
Pages
686
Book Type
Professional

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