This chapter discusses about minimally invasive kidney transplantation which reduces perioperative morbidity, incision, surgical site infection, blood loss, postoperative pain, hospital stay and convalescence period. Being fragile and immunocompromised, patients undergoing kidney transplantation are at a higher risk for developing perioperative complications than the renal donor. Instruments used in minimally invasive kidney transplantation include robotic instruments and ports, laparoscopic instruments such as microfrance laparoscopic grasper, suture passer, or bulldog clamps with appliers, disposables, and slush machine drape. Surgical techniques include preparation of patient positioning, port placement, preparation of the vascular bed, donor graft, venous anastomosis, and ureteroneocystostomy. A venotomy is made using cold scissors. The graft renal vein is anastomosed in an end-to-side continuous fashion to the EIV using an ePTFE suture. Early outcomes achieved with RKT are at par with the outcomes achieved with the conventional open technique, with a propensity towards reduced complications and lower morbidity.