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Chapter-65 Overview

BOOK TITLE: Kidney & Pancreas Transplantation

Author
1. Nicastro Jeffrey M.
2. Coppa Gene F.
3. Molmenti Ernesto P
4. Molmenti Christine Sardo
5. Gruessner Angelika
6. Gruessner Christine E
7. Gruessner Stefan A
8. Rilo Horacio
9. Gruessner Rainer
ISBN
9789351523390
DOI
10.5005/jp/books/12547_66
Edition
1/e
Publishing Year
2015
Pages
4
Author Affiliations
1. Hofstra North Shore – LIJ School of Medicine and North Shore – Long Island Jewish Health System, New York, USA
2. Hofstra North Shore – LIJ School of Medicine, New York, USA
3. Hofstra Northwell School of Medicine, Long Island, New York, USA, North Shore-LIJ Health System, Long Island, New York, USA; Hofstra North Shore–LIJ School of Medicine, Long Island, New York, USA
4. Mailman School of Public Health, Herbert Irving Comprehensive Cancer Center, New York-Presbyterian Columbia University Medical Center, New York, USA
5. Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA
6. University of Arizona, Tucson, Arizona, USA
7. University of Arizona, Tucson, Arizona, USA
8. Cell Transplant Institute; Arizona Diabetes Center, University of Arizona School of Medicine, Tucson, Arizona, USA
9. University of Arizona, Tucson, Arizona, USA
Chapter keywords
pancreas transplantation, normoglycemia, insulin independence, hemoglobin A1c levels, simultaneous pancreas kidney (SPK) transplantation, pancreas after kidney (PAK) transplantation, and pancreas transplantation alone (PTA), hyperglycemia, brain dead donor

Abstract

The chapter presents an overview on pancreas transplantation. The main goals of pancreas transplantation are insulin independence and normoglycemia with normal hemoglobin A1c levels, prolonged survival and improved quality of life. It is categorized into three parts, namely 1) simultaneous pancreas kidney (SPK) transplantation, 2) pancreas after kidney (PAK) transplantation, and 3) pancreas transplantation alone (PTA). When considering potential deceased donors, the accepting surgeon should determine the likelihood of function after implantation based on donor quality. Hyperglycemia in a brain dead donor does not constitute by itself a contraindication to pancreatic procurement. A history of diabetes in the donor should always be excluded.

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