This chapter discusses the future of rhinology, where first-line therapy for allergic rhinitis remains topical corticosteroid sprays and currently, over 16 different nasal steroid sprays are commercially available. Two of the benefits of endoscopic sinus surgery are postoperative sinus debridement and drainage with better delivery of topical medications to diseased mucosa. Aerosolized microparticles are more likely to coat the entire surface area of the sinuses with less residual to later drain from the nose. Biofilms play a significant role in the manifestation of many otorhinolaryngologic illnesses. Treating topically prepared nasal and paranasal sinus mucosa with selective laser light exposure effectively destroys biofilms while preserving normal tissue and reducing the need for antibiotics. Advantages of robotic surgery include three dimensional visualization, tremor and fine motor scaling, and increased magnification. Vanderbilt is currently developing a robot system that uses concentric tubing to provide tentaclelike movements from robotic arms.