Pregnancy and puerperium are associated with pulmonary embolism and is a significant cause of pregnancy-related morbidity and mortality. Clinical features of PE are not different from those in the nonpregnant state. Therefore clinical diagnosis and development of PE in pregnancy is difficult due to the same signs and symptoms. American Thoracic Society/Society of Thoracic Radiology Clinical Practice recommended some guidelines for the diagnosis, risk assessment, stratification etc., in pregnancy. Diagnosis procedures such as amniotic fluid embolus and chorion carcinoma, disseminated vascular coagulopathy are used. It is recommended that Low-risk patients should take low-dose aspirin once daily from pregnancy until delivery, because aspirin reduces the incidence of DVT and PE. For prevention of death from PE during it is necessary to adopt accurate diagnostic tests, approaches and appropriate therapy.