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Chapter-015 Ethnopharmacy in Diabetes

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Kalra Sanjay
2. John Mathew
ISBN
9789351526476
DOI
10.5005/jp/books/12535_22
Edition
2/e
Publishing Year
2015
Pages
3
Author Affiliations
1. Bharti Hospital, Karnal, Haryana, India, Bharti Hospital and B.R.I.D.E., Karnal 132 001, Haryana, India, Bharti Hospital and BRIDE Karnal; Indian J Endocrinology Metabolism, Bharti Hospital, Karnal, Haryana, India, Bharti Hospital, Karnal-132001, Haryana, India, Indian J Endocrinology and Metabolism; J of Social Health in Diabetes (JoSH Diabetes), Bharti Hospital and BRIDE, Karnal, Haryana, India, Bharti Hospital and BRIDE, Karnal, Haryana, India
2. Providence Endocrine and Diabetes Speciality Centre, Trivandrum, Providence Endocrine and Diabetes Specialty Centre, Trivandrum, Kerala, India
Chapter keywords
Ethnopharmacy, UKPDS, HbA1c, type-2 diabetes, glycemic control, DiabCare Asia

Abstract

This chapter mainly focuses the current guidelines in management of hyperglycemia from ethnopharmacy perspective. The existence of type-2 diabetes is increasing in epidemic proportions in low- to middle-income countries. United Kingdom Prospective Diabetes Study (UKPDS) proved that strict glycemic control reduces both microvascular and macrovascular complications. DiabCare Asia study has carried out to find the mean HbA1c among 12 different Asian countries. The use of basal insulin/insulin analogs as the start-up insulin is recommended by the ADA/EASD consensus statement. Insulin resistance, dietary pattern, glucose metabolism and genetic variation depends on the racial and ethnicity. Hence ethnopharmacy perspective based guidelines should be used for the proper evaluation. Characteristics of type-2 diabetes vary from Asian populations to European populations. The higher insulin responses, increased insulin resistance and insulin sensitivity are some of the pathophysiology of diabetes which varies according to the ethnicity. Diabetes therapies also differ based on ethnic variations.

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