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Chapter-031b Vitamin D and Diabetes Emerging Links

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Gupta Rajat
ISBN
9789351526476
DOI
10.5005/jp/books/12535_39
Edition
2/e
Publishing Year
2015
Pages
3
Author Affiliations
1. Fortis Escorts Heart Institute, New Delhi, India, Alchemist Hospital, Panchkula, Haryana, India, Alchemist Hospital, Panchkula, Haryana, Delhi, Skinnovation Clinics and Excel Medical Centers, New Delhi, India, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
Chapter keywords
Vitamin D deficiency, autoimmune disorders, type 1 diabetes, type 2 diabetes, Th1 cytokines, cholecalciferol, cardiometabolic disorders

Abstract

This chapter emphasizes the importance of vitamin D and its role in diabetes. Vitamin D is an essential nutrient that plays a vital role in calcium metabolism and bone health. Vitamin D deficiency (VDD) is associated with increased prevalence of malignancies, type 1 diabetes, multiple sclerosis and various cardiometabolic disorders. Vitamin D synthesized in skin and derived from diet is biologically inactive and they must be activated to exert its effects. Several studies has been reported the role of vitamin D in the prevention and treatment of both type 1 and type 2 diabetes. This is achieved through actions of vitamin D on systemic inflammation, insulin secretion and insulin resistance. The daily dietary requirement of vitamin D as cholecalciferol in various age groups is briefly explained.

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