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Chapter-031b Vitamin D and Diabetes Emerging Links

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Gupta Rajat
ISBN
9789351526476
DOI
10.5005/jp/books/12535_39
Edition
2/e
Publishing Year
2015
Pages
3
Author Affiliations
1. Fortis Escorts Heart Institute, New Delhi, India, Alchemist Hospital, Panchkula, Haryana, India, Alchemist Hospital, Panchkula, Haryana, Delhi
Chapter keywords
Vitamin D deficiency, autoimmune disorders, type 1 diabetes, type 2 diabetes, Th1 cytokines, cholecalciferol, cardiometabolic disorders

Abstract

This chapter emphasizes the importance of vitamin D and its role in diabetes. Vitamin D is an essential nutrient that plays a vital role in calcium metabolism and bone health. Vitamin D deficiency (VDD) is associated with increased prevalence of malignancies, type 1 diabetes, multiple sclerosis and various cardiometabolic disorders. Vitamin D synthesized in skin and derived from diet is biologically inactive and they must be activated to exert its effects. Several studies has been reported the role of vitamin D in the prevention and treatment of both type 1 and type 2 diabetes. This is achieved through actions of vitamin D on systemic inflammation, insulin secretion and insulin resistance. The daily dietary requirement of vitamin D as cholecalciferol in various age groups is briefly explained.

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