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Chapter-004 Type 1.5 Diabetes

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Bandgar Tushar R
2. Kalra Sanjay
ISBN
9789351526476
DOI
10.5005/jp/books/12535_5
Edition
2/e
Publishing Year
2015
Pages
5
Author Affiliations
1. Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India
2. Bharti Hospital, Karnal, Haryana, India, Bharti Hospital and B.R.I.D.E., Karnal 132 001, Haryana, India, Bharti Hospital and BRIDE Karnal; Indian J Endocrinology Metabolism, Bharti Hospital, Karnal, Haryana, India, Bharti Hospital, Karnal-132001, Haryana, India, Indian J Endocrinology and Metabolism; J of Social Health in Diabetes (JoSH Diabetes), Bharti Hospital and BRIDE, Karnal, Haryana, India, Bharti Hospital and BRIDE, Karnal, Haryana, India
Chapter keywords
Autoantibodies, hirsute, balanoposthitis, ketonuria, arthritis, sulfonylureas

Abstract

This chapter focuses on type 1.5 diabetes. Diabetes mellitus is a vast syndrome that comprises a diverse range of clinical conditions. Various classifications of diabetes that are used do not mention the term “type 1.5 diabetes”. Yet there are a sizeable number of subjects with diabetes, who do not fit into the watertight compartments of type 1 or type 2 diabetes. This chapter covers two subgroups of such patients, who may be described as having type 1.5 diabetes. The patients may be termed as having type 1.5 diabetes, as they initially behave as type 1 (ketosis prone), converting later into type 2 diabetes. Its etiopathogenesis, clinical features, diagnosis, treatment and prognosis are well explicated. Early recognition of latent autoimmune diabetes in adults and ketosis-prone type 2 diabetes avoids misunderstanding on the part of patients, relatives and health care professionals. It can help in the timely institution of correct therapy, as well as optimal patient counseling. This, in turn, will help prevent the multiple complications associated with the poor glycemic control.

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