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Chapter-059 Radiotherapy of the Pituitary

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. John Subhashini
ISBN
9789351526476
DOI
10.5005/jp/books/12535_74
Edition
2/e
Publishing Year
2015
Pages
8
Author Affiliations
1. Christian Medical College, Villero, Tamil Nadu, India
Chapter keywords
Radiotherapy, pituitary tumors, endocrine active, endocrine inactive, pituitary adenomas, hypopituitarism, radiation necrosis, cerebral infarction

Abstract

Pituitary tumors have low proliferative activity and constitutes for about 10-15% of all the brain tumors. Based on the secretary potential as endocrine active or endocrine inactive, pituitary glands are classified. The main modality of treating pituitary adenomas is resection because it results in rapidly achieving the goals of the therapy with instant decompression of tumor and mass effects and also improving the lost function. The different radiotherapy techniques are: conventional radiotherapy, high precision radiotherapy, and intensity modulated radiation therapy (IMRT). The most common complications that occur after the radiotherapy is hypopituitarism and it is found to be doe related. Other complications are: loss of vision, carcinogenesis, radiation necrosis, and cerebral infarction. The outcome of the treatment is reported in the form of disease free survival (DFS), progression free survival (PFS), local control (LC), reduction in hormone levels and complications.

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