Women’s health over her whole life span poses unique challenges. Women account for nearly half of the people with diabetes and more recent data have shown that prediabetes is more frequent in women and more women die of diabetes than men. The dramatic rise in the prevalence of diabetes in women has been linked to the elevating prevalence of obesity. Major reasons for obesity and diabetes in women are sedentary lifestyle, television watching, genetic predisposition, stress, etc. Women with type 1, and type 2 diabetes are at high risk for bone loss and fractures. Diabetes affects women of all ages and predominantly women in the middle and lower socioeconomic regions of the world. This poses great public health tasks and burdens the system. A well planned, gender sensitive, women centric approach that will delegate the women, train healthcare workers and sensitize the policy makers is urgently required.