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Chapter-073b Diagnosis of Osteoporosis and Assessment of Fracture Risk

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Bansal Beena
ISBN
9789351526476
DOI
10.5005/jp/books/12535_91
Edition
2/e
Publishing Year
2015
Pages
5
Author Affiliations
1. Medanta – The Medicity, Gurgaon, Haryana, India, Medanta - The Medicity, Gurgaon 122 001, Haryana, India, Medanta–The Medicity, Gurgaon, Haryana, India, Medanta, the Medicity, Gurgaon, Haryana, India, Medanta - The Medicity, Gurgaon, Haryana, India
Chapter keywords
Dual X-ray absorptiometry, peripheral dual-energy X-ray absorptiometry, CT-based absorptiometry, quantitative ultrasound densitometry, bone marker, FRAX

Abstract

Bone densitometry revolutionized the field of osteoporosis. Dual X-ray absorptiometry is used for measures the bone mass per unit area or areal density. It is a very costly scan. The main advantage of DXA is that it exposes patients to only very low levels of radiation. But it is not available at all medical centers and is also expensive. Peripheral dual-energy X-ray absorptiometry (pDXA), CT-based absorptiometry and Quantitative ultrasound densitometry (QUS) are also used for measure the bone density. Bone markers are generally classified as markers of bone formation and markers of bone resorption, but since both these processes are coupled. In general, bone markers reflect overall bone turnover. Bone mass and fracture are related to each other same as that between blood pressure and stroke. The fracture risk assessment tool (FRAX) is used to predict the fracture risk.

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