EXPORT CITATION

Chapter-083 Gynecomastia

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Muraleedharan MV
ISBN
9789351526476
DOI
10.5005/jp/books/12535_102
Edition
2/e
Publishing Year
2015
Pages
3
Author Affiliations
1. Amrita Institute of Medical Sciences, Amrita Lane, Elamakkara Post, Kochi, Kerala, India, Medical College, Thrissur, Andhra Pradesh, India, Government of Kerala, Trivandrum, Kerala, India
Chapter keywords
Gynecomastia, lipomastia, breast carcinoma, acinar proliferation, anti-androgens, anabolic steroids, tricyclic antidepressants

Abstract

Gynecomastia is defined as the gentle proliferation of male breast glandular tissue, and is generally caused by improved estrogen activity. Actions of estrogen on breast tissue contain proliferation of ductal epithelium, elongation of a duct, stromal edema, and fibrosis. Drugs are probable to be helpful if used in the active phase of the disease. When making physical examination, true gynecomastia should be differentiated from such as lipomastia and breast carcinoma. The role of prolactin in the causation of gynecomastia if any is circuitous by producing central hypogonadism. Pathogenesis of transforming growth factors, epidermal growth factor, and platelet-derived growth factor, their function in the causation of gynecomastia is not clear. Drugs are important causes of gynecomastia. Laboratory evaluation and treatment is necessary if there is pain or psychosocial embarrassment. When drugs are not effective, surgery can be done.

Related Books

© 2019 Jaypee Brothers Medical Publishers (P) LTD.   |   All Rights Reserved

Powered by MPS ScholarStor