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Chapter-089a Growth Hormone Disorder: Approach to Short Stature

BOOK TITLE: ESI Manual of Clinical Endocrinology

Author
1. Acharya Shrikrishna V
2. Gopal Raju
ISBN
9789351526476
DOI
10.5005/jp/books/12535_108
Edition
2/e
Publishing Year
2015
Pages
8
Author Affiliations
1. NMC Speciality Hospital, Abu Dhabi
2. Baby Memorial Hospital, Kozhikode, Kerala; MES Medical college, Perinthalmanna, Kerala, India
Chapter keywords
Pseudohypoparathyroidism, juvenile rheumatoid arthritis, tachycardia, tachypnea, congenital heart disease, Growth hormone disorder, Bone age radiography

Abstract

Short stature or growth retardation is considered as sign of poor health. History is important in establishing the cause of a child’s short stature such as antenatal history, birth history, family history, dietary history and medical history. Growth record provides important provides the correct diagnosis. Growth velocities depend on the age and pubertal status. Short stature is explained on the basis of body proportion. Target of height depends on bone age. In general examinations, tachycardia examined the cardiac failure, tachypnea may be observed in respiratory disorders such as cystic fibrosis, Joint swellings and rash are present in juvenile idiopathic arthritis etc. In systemic examination, congenital heart disease associated with genetic disorders. Laboratory evaluation is based on the physical examinations and history such as complete blood count, BA X-ray, Insulin-like growth factor 1 (IGF-1) and IGF-binding protein 3 to screen for GH deficiency etc. the differential diagnosis of pathological short stature is to divide patients into those with dysmorphic features and those without.

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