This chapter discusses carotid artery stenting through radial access. In western countries, stroke affects approximately 0.2% of the population annually. About 90% of the strokes are ischemic and 10% are hemorrhagic. The major cause of stroke is large-vessel atherosclerosis, with the highest risk occurring in patients with stenosis of the internal carotid arteries. The main advantage of the radial access is the low rate of major vascular complications, increased comfort due to the ability to sit up after the procedure and the fast mobilization which results in shortened hospitalization. Equipment for transradial CAS, technique, and complications are covers in this chapter. Neurologic complications include transient ischemic attacks, minor strokes, and consequent deaths. Radial artery spasm is a common problem and in most of the cases can be prevented with intra-arterial vasodilators and/or hydrophilic guidewires.