This chapter mainly focuses on the complications of vitiligo surgery. Complications in vitiligo surgery include those which are specific to the technique and those which are common to any surgery. Some complications are common to any surgery such as reactions to anesthetic agents, infections, keloid formation, etc. To avoid these complications, the surgery should be performed in an operation theater setting, with all aseptic precautions to avoid infection. Presence of infection will not only lead to graft failure, but can also lead to scarring. Bleeding and oozing from the donor site can occur, particularly over a large area. A pressure dressing, with layers of gauze pad and adhesive bandage will minimize this side effect. Specific complications, color mismatch (hyperpigmentation and hypopigmentation), perigraft halo and achromic fissures, cobblestoning (raised grafts) and sunken pits (sunken grafts), graft hypertrophy, etc. are also discussed in this chapter.