This chapter explains about the dynamic volume status indicators. Most of the patients admitted in a hospital require intravenous (IV) fluid administration, which is given empirically or depending upon clinical signs. Basic patient measures like skin turgor, heart rate, blood pressure, urine output, central venous pressure, and peripheral oxygen saturation are unreliable in detecting hypovolemic or hypervolemic states. Stroke volume variation (SVV) is the natural fluctuation in stroke volume during a ventilatory cycle. Stroke volume variation is a result of the changes in intrathoracic pressure during respiration. In the spontaneously breathing patient, during inspiration, SV falls as a result of negative intrathoracic pressure impeding ventricular emptying. Stroke volume variation can be used in both the operating room and intensive care unit (ICU) for patients who are receiving positive pressure ventilation. Pulse pressure variation, systolic pressure variation, aortic blood flow peak velocity, superior vena cava collapsibility index, inferior vena cava collapsibility index or caval index, the end-expiratory occlusion, passive leg raise test, etc. are some other important topics also covered in this chapter.