This chapter describes an approach to epistaxis. Epistaxis is defined as bleeding from nose or nasopharynx. Epistaxis has bimodal age distribution and is most commonly seen under the age of 10 years and over 40 years. There is no race or gender predilection. This chapter covers the epidemiology, relevant anatomy, etiology, investigations, imaging, management, and prevention. Epistaxis can be classified depending on anatomical location, onset, severity, causing, risk factors, and age as anterior or posterior, primary or secondary, traumatic or nontraumatic, acute or chronic, and pediatric or adult. The most common cause of epistaxis in children is digital trauma and hypertension in people over 40 years of age. It is frequently seen in dry season and in less humid environments.