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Chapter-26 Drugs Acting on Uterus

BOOK TITLE: Drug Formulary

Author
1. George Mathew
2. Joseph Lincy
3. K Sujith
ISBN
9789352701896
DOI
10.5005/jp/books/14188_27
Edition
1/e
Publishing Year
2018
Pages
6
Author Affiliations
2. Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
3. Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
Chapter keywords
Uterus, oxytocin, isoxsuprine, carboprost, danazol, methylergometrine, valethamate

Abstract

This chapter describes drugs acting on uterus, which include oxytocin, isoxsuprine, carboprost, danazol, methylergometrine, and valethamate. Adjunct in abortion, postpartum hemorrhage, labor induction, oxytocin challenge test for evaluating of fetal distress are the indication of oxytocin. Cephalopelvis disproportion, abnormal presentation of the fetus, hydraminios, multiparae, previous cesarean section or other uterine surgery, hyperactive or hypertonic uterus, and uterine rupture are the contraindications of oxytocin. Endometriosis, benign breast disorders, hereditary angioedema, gynecomastia, preoperative thinning of the endometrium, and menorrhagia are the indication of danazol.

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