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Chapter-34 Immunosuppressants

BOOK TITLE: Drug Formulary

Author
1. George Mathew
2. Joseph Lincy
3. K Sujith
ISBN
9789352701896
DOI
10.5005/jp/books/14188_35
Edition
1/e
Publishing Year
2018
Pages
2
Author Affiliations
1. Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
2. Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
3. Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
Chapter keywords
Immunosuppressant drug, azathioprine, hypersensitivity, renal transplant rejection, rheumatoid arthritis, autoimmune disease, pregnancy, lactation

Abstract

Immunosuppressant drugs are a class of drugs that suppress, or reduce, the strength of the body’s immune system. Some of these drugs are used to make the body less likely to reject a transplanted organ, such as a liver, heart, or kidney. This chapter covers the azathioprine along with their indication, dose, contraindication, precaution, adverse effect, and drug interaction. Renal transplant rejection, adjunct, prophylaxis, rheumatoid arthritis, and autoimmune diseases are the indications of azathioprine. Hypersensitivity, previous treatment with alkylating agents, pregnancy, and lactation are the contraindications of azathioprine.

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