This chapter describes patient advice. These are importance of advising patients of anticipated menstrual effects, importance of using caution, when driving or operating machinery, especially during the initiation of therapy, Importance of discontinuing therapy and contacting clinician if sudden partial or complete vision loss, blurred vision, bulging of the eyes, double vision, or migraine occur, importance of discontinuing therapy and contacting clinician if any symptoms of thromboembolic and thrombotic disorders occurs, importance of women informing clinicians if they are or plan to become pregnant or plan to breastfeed, importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and over-the counter (OTC) drugs, as well as concomitant illnesses.