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Chapter-10 Cordocentesis

BOOK TITLE: Ultrasound Guided ‘Invasive Prenatal Diagnostic Techniques’ Simplified

Author
1. Sahetya Raju R
ISBN
9789352702336
DOI
10.5005/jp/books/14151_11
Edition
1/e
Publishing Year
2018
Pages
4
Author Affiliations
1. Mumbai, Maharashtra, India, A Postgraduate from Seth GS Medical College, Mumbai, Maharashtra, India, Indian Society for Prenatal Diagnosis and Therapy (ISPAT); Pushpaa Hospital, Hinduja Hospital, Mumbai, Maharashtra, India
Chapter keywords
Cordocentesis, fetal blood sampling, fetal bradycardia, bleeding, cord blood sampling, chorionic villous sampling, CVS, amniocentesis

Abstract

Cordocentesis as a method of fetal blood sampling was first carried out in the 1960s under fetoscopic guidance and carried a procedure-related fetal loss rate of over 5%. The first percutaneous umbilical cord sampling under ultrasound control was reported by Daffos et al. In 1983 this development revolutionized the technique, allowing access to the fetal vascular compartment for both diagnostic and therapeutic means, with a procedure-related fetal loss rate of less than 2%. The major complications of cordocentesis are fetal bradycardia, bleeding at the puncture site or occasionally asystole. The world experience of cordocentesis is much smaller than for other invasive techniques such as chorionic villous sampling (CVS) or amniocentesis.

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