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Chapter-10 New Insights into Pigment Dispersion Syndrome and Pigmentary Glaucoma

BOOK TITLE: Gems of Ophthalmology—Glaucoma

Author
1. Jr Maris PJG
2. RK Bansal
ISBN
9789352702497
DOI
10.5005/jp/books/18037_11
Edition
1/e
Publishing Year
2018
Pages
11
Author Affiliations
1. Edward S Harkness Eye Institute, Columbia University Medical Center, NYC, New York, USA
2. Edward S Harkness Eye Institute, Columbia University Medical Center, NYC, New York, USA
Chapter keywords
Pigmentary glaucoma, pigment dispersion syndrome, Laser trabeculoplasty, LT, intraocular lens, IOL, peripheral anterior synechiae, PAS, pseudoexfoliation syndrome, PXS, prostaglandin

Abstract

Pigmentary glaucoma is a secondary open-angle glaucoma characterized by homogenous brownish pigmentation of the chamber angle, pigment deposition on the corneal endothelium (the ‘Krukenberg spindle’) and slit-like, radial, midperipheral transillumination defects of the iris. The pathophysiology of PG considers two major mechanisms following as the mechanics of pigment dispersion and obstruction of aqueous outflow. This chapter covers the demographics and symptoms, clinical exam findings, differential diagnosis, and management. Pigmentary glaucoma is typically seen in myopic, young adult males. Medical treatment is similar to other forms of open-angle glaucoma. Regarding laser treatment, future research will better elucidate the most efficacious and safe modalities, including laser trabeculoplasty and peripheral iridotomy.

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