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Chapter-10 Changing Trends in Management of Carcinoma of Gallbladder

BOOK TITLE: Gastrointestinal Surgery Series: Pancreas and Hepatobiliary Surgery

Author
1. Khanna Seema
2. Shukla VK
ISBN
9789352702602
DOI
10.5005/jp/books/14149_11
Edition
1/e
Publishing Year
2018
Pages
8
Author Affiliations
1. Institute of Medical Sciences, Banaras Hindu University, Varanasi, India, Institute of Medical Sciences, Banaras Hindu University Varanasi (UP), India, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
2. Institute of Medical Sciences, Banaras Hindu University, Varanasi, India, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
Chapter keywords
Gallbladder cancer, incidental gallbladder cancer, lymph node status, adjuvant therapy, Tis gallbladder carcinoma, Tia gallbladder carcinoma, laparoscopic cholecystectomy, tumor node metastasis, TNM

Abstract

Gallbladder cancer is an aggressive tumor with a poor prognosis. The incidence peaks at 70–75 years, with a female preponderance (3:1, female:male ratio). There is a strong correlation with gallstones and longer duration of cholelithiasis and larger size of stone (>3 cm) further increases the risk. The majority (60%) of gallbladder cancers arise in the fundus of the gallbladder, 30% occur in the body, and 10% in the neck. The extent of the gallbladder cancer and the mode of its detection decide the treatment modality. With laparoscopic cholecystectomy becoming the gold standard for treating gallstones, the incidental discovery of gallbladder carcinoma peroperatively or postoperatively on histopathology is a new phenomenon, which needs to be addressed. This chapter covers the Tis and Tia gallbladder carcinoma, incidental gallbladder cancer, lymph node status, and adjuvant therapy.

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