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Chapter-21 Sedatives/Hypnotics

BOOK TITLE: Pharmacology for Medical Undergraduates

Author
1. Bhandari Prasan R
ISBN
9789352702718
DOI
10.5005/jp/books/14244_22
Edition
1/e
Publishing Year
2018
Pages
8
Author Affiliations
1. SDM College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka, India, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India
Chapter keywords
Sedatives, hypnotics, benzodiazepines, barbiturates, BZD antagonist, antianxiety agent

Abstract

This chapter presents discussion on sedatives/hypnotics. Sedatives produces calming/quietening actions, decreases excitement, produces drowsiness. Hypnotic induces sleep mimicking natural sleep. Both sedation and hypnosis are different grades of central nervous system (CNS) depression. Gamma-aminobutyric acid (GABA) is the principle inhibitory neurotransmitter in CNS. Pharmacological actions, advantages, adverse drug reaction, and uses of benzodiazepines (BZDs) have been covered in this chapter. A detailed description on barbiturates and antianxiety agents has been also given in this chapter.

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