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Chapter-35 Hematinics

BOOK TITLE: Pharmacology for Medical Undergraduates

Author
1. Bhandari Prasan R
ISBN
9789352702718
DOI
10.5005/jp/books/14244_36
Edition
1/e
Publishing Year
2018
Pages
7
Author Affiliations
1. SDM College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka, India, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India
Chapter keywords
Hematinics, anemia, iron deficiency, iron metabolism, iron preparation, maturation factor, vitamin B12, folic acid, erythropoietin, hematopoietic growth factor, myeloid growth factor

Abstract

This chapter covers discussion on hematinics. They are the drugs/substances that increase hemoglobin level in the blood. These include iron, folic acid, vitamin B12, pyridoxine, ascorbic acid, riboflavin, copper or erythropoietin (from kidneys). All the elemental iron present is not absorbed. Absorption varies from preparation to preparation. Ferrous salts are absorbed better. Rate and extent of absorption also depends on deficiency of the hemoglobin. Absorption is more when deficiency is more. Acidic pH and vitamin C enhances absorption of iron. Folic acid is a combination of glutamic acid, para-aminobenzoic acid, and pteridine nucleus. Hematopoietic growth factors stimulate growth and differentiation of blood cells, for example, erythropoietin, thrombopoietin, myeloid growth factors.

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