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Chapter-41 Hypothalamic and Pituitary Hormones

BOOK TITLE: Pharmacology for Medical Undergraduates

Author
1. Bhandari Prasan R
ISBN
9789352702718
DOI
10.5005/jp/books/14244_42
Edition
1/e
Publishing Year
2018
Pages
5
Author Affiliations
1. SDM College of Medical Sciences and Hospital, Sattur, Dharwad, Karnataka, India, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India
Chapter keywords
Hormone, growth hormone-releasing hormone, somatostatin, thyrotropin-releasing hormone, corticotropin-releasing factor, gonadotropin-releasing hormone, anterior pituitary hormone, prolactin

Abstract

Hormone is substance produced by specialized cells in specific glands and transported in circulation to distance where it acts on target tissues. Peptides, steroids, catecholamines, etc. are some types of hormones. Growth hormone-releasing hormone (GHRH) stimulates anterior pituitary to secrete growth hormone. Sermorelin is GHRH analogue used to diagnose growth hormone (GH) deficiency. Somatostatin is present in hypothalamus, parts of central nervous system (CNS), pancreas and gastrointestinal tract (GIT). It inhibits secretion of GH, thyroid stimulating hormone (TSH), prolactin (PRL), insulin, glucagon and intestinal secretions. Thyrotropin-releasing hormone, corticotropin-releasing factor, gonadotropin-releasing hormone, etc. are other hypothalamic hormones which are mentioned in this chapter. A detailed discussion on anterior pituitary hormones has been also presented in this chapter.

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