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Chapter-06 Endocrinal Causes of Recurrent Spontaneous Miscarriages

BOOK TITLE: Recurrent Spontaneous Miscarriages

Author
1. Desai Pankaj
ISBN
9789352702763
DOI
10.5005/jp/books/18032_7
Edition
3/e
Publishing Year
2018
Pages
21
Author Affiliations
1. Medical College, Baroda, Janani Maternity Hospital, Baroda, Medical College and SSG Hospital Baroda, Medical College, Baroda, India, Medical College and SSG Hospital, Baroda, Gujarat, (Unit IV), Medical College and SSG Hospital, Baroda, Medical College and SSG Hospital, Vadodara, Gujarat, India, Medical College and SSG Hospital, Baroda, Dept of Obs and Gyn Medical College, Baroda, Medical College and SSG Hospital, Baroda, India, FOGSI; Janani Maternity Hospital, Baroda, India, Vadodara, Medical College, Baroda, Gujarat, India, Janani Maternity Hospital, Baroda, Gujarat, India, Medical Collage and SSG Hospital, Vadodara, Gujarat, India, Baroda, Gujarat, India, Baroda, Medical College, Vadodara, Gujarat, India, Baroda Medical College and Sir Sayajirao General Hospital, Vadodara, Gujarat, India, Janani Maternity Hospital, Vadodara, Gujarat, India; Medical College and SSG Hospital, Vadodara, Gujarat, India; Societies of India (FOGSI), 2007, Medical College, SSG Hospital and Baroda, Gujarat, India
Chapter keywords
Endocrinal cause, recurrent spontaneous miscarriage, luteal phase deficiency, hyperprolactinemia, polycystic ovarian syndrome, PCOS, thyroid disease, hypoparathyroidism, uncontrolled diabetes

Abstract

This chapter focuses on endocrinal causes of recurrent spontaneous miscarriages. Following implantation, the maintenance of the pregnancy is dependent on a multitude of endocrinological events that will eventually aid in the successful growth and development of the fetus. Although the vast majority of pregnant women have no preexisting endocrine abnormalities, a small number of women can have certain endocrine alterations that could potentially lead to recurrent spontaneous miscarriages. Luteal phase deficiency, hyperprolactinemia, and polycystic ovarian syndrome (PCOS) are some examples of endocrinal disorders that can disrupt a healthy pregnancy. Several other endocrinological abnormalities such as thyroid disease, hypoparathyroidism, uncontrolled diabetes, and decreased ovarian reserve have been implicated as etiological factors for recurrent spontaneous miscarriages. This chapter reviews current evidence on the role of endocrinology in recurrent pregnancy miscarriages.

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