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BOOK TITLE: Retina: Medical and Surgical Management
This chapter gives an overview on electrophysiology. Visual electrophysiological tests are objective tests that help to assess the functional integrity of visual pathway, starting from photoreceptor and retinal pigment epithelial layer in retina to the occipital cortex. Electroretinography (ERG), multifocal ERG (mfERG), electrooculography, visual evoked potential (VEP), and pattern VEP are different types of visual electrophysiological tests. ERG measures the electrical activity generated by the retina in response to light. This is measured at the level of the cornea as there exists a potential difference between the cornea and retina known as corneoretinal potential (range 0.4– 1 mV). mfERG as the name suggests, is a method of recording local electrophysiological responses from different regions of the retina. The VEP is the measure of cortically evoked electrical activity and is in fact an electroencephalogram recording of the occipital lobe and is a measure of the integrity of the visual pathway.