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Chapter-056 Diabetic Hypertriglyceridemia: Management Strategies

BOOK TITLE: Cardiodiabetes Update: A Textbook of Cardiology

Author
1. Chopra HK
2. Singh Harmeet
3. Jaiswal Ashok
ISBN
9789352703043
DOI
10.5005/jp/books/14130_57
Edition
1/e
Publishing Year
2018
Pages
8
Author Affiliations
1. Moolchand Medcity Hospital, New Delhi, India, Medanta Moolchand Heart Institute, Moolchand Medcity, New Delhi, India, Medanta Moolchand Heart Institute, Moolchand Medcity; World Wellness Foundation, WHA; AHA, Medanta Moolchand Heart Institute; Moolchand Medcity; World Wellness Foundation, WHA; CSI & IAE; IHJ, JIAE, Medanta Moolchand Heart Institute; Moolchand Medcity; World Wellness Foundation, WHA, Medanta Moolchand Heart Institute, New Delhi, India; CME, Moolchand Medcity, World Wellness, Foundation and WHA; AHA; CSI and IAE; IHJ and JIAE, IAE-2017, CSI-2015; World Wellness Foundation, Country Head, American Heart Association; Medanta Moolchand Heart Institute; Health Committee, SCOPE, Tata Sky FAM Health, New Delhi, India, IAE- 2017, CSI -2015; World Wellness Foundation; American Heart Association; Moolchand Medcity; Physician Governing Body, CME, COP Moolchand Medcity, New Delhi, India, IAE- 2017, CSI -2015; World Wellness Foundation; Physician Governing Body, CME, COP Moolchand Medcity, New Delhi, India
2. Moolchand Medcity, New Delhi, India
3. Zydus Recovery, Ahmedabad, Gujarat, India
Chapter keywords
Diabetes, hypertriglyceridemia, atherogenic diabetic dyslipidemia, ADD, hyperglycemia, adipocytokine, insulin deficiency, lifestyle management

Abstract

In diabetes, hypertriglyceridemia is rarely observed alone, rather, it is a combination of hypertriglyceridemia, low HDL-C and high levels of sdLDL-C levels that are generally observed and termed as “atherogenic dyslipidemia” or “atherogenic diabetic dyslipidemia (ADD)”. In diabetes, there are multiple factors that influence the changes in lipid metabolism, like hyperglycemia, adipocytokines, and insulin deficiency or resistance. Lifestyle management is the first and foremost intervention in the management of diabetic dyslipidemia, with the main aim of losing weight through dietary modification and exercising more. Diabetic hypertriglyceridemia can be partially rectified by insulin therapy and better blood glucose control. Insulin therapy tends to elevate HDL cholesterol and decrease the circulating TG levels, particularly in patients with poor glycemic control.

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