JaypeeDigital | Lixisenatide: A Cardiodiabetes Perspective

TESTIMONIALS

Ozlem YALCINKAYA Library Director, Bezmialem Vakif University, Turkey

Many thanks to JAYPEEDIGITAL platform, which has been an indispensable easy-to-use source for our...

Dr Jesus Tapia Jurado Chief- Surgery Depatment, Faulty of medicine, Unversidad Nacional Autonoma de Mexico(UNAM) Mexico DF, Mexico

Jaypeedigital site offers to our students a huge number of medical publications such as textbooks...

Wan Suhaimi Ariffin, MLS (Syracuse), BLS (UITM)` Head, The National University of Malaysia (UKM), Medical Centre Library, Kuala Lumpur, Malaysia

With user-friendly interface, Jaypeedigital provides extensive coverage in medicine, dentistry and...

David E. García Díaz (MD) Head, Physiology Department, Faculty of Medicine, Universidad Nacional Autónoma de México DF, Mexico

Jaypeedigital platform presents an interesting and valuable collection of medical publications that...

Arcelia Meléndez Ocamp (MD) Head, Preventive Dentistry & Public Health Department, Universidad Nacional Autónoma de México DF, México

Some of us teach in the Division of Graduate Studies and Research at the Faculty and the contents of...

Dra. Blanca Alicia Chong Martínez Jefe de Educación Médica Continua Head of Basic Science and Continuous Medical Education Facultad Mexican de Medicina (ULSA)

It is a very complete and up-to-date platform that could be applied to all levels of the Medicine...

NEWSLETTERS

Subscribe to be the first to know about Best Deals and Exclusive Offers!

Share This Title

GET ACCESS EXPORT CITATION

Chapter-063 Lixisenatide: A Cardiodiabetes Perspective

BOOK TITLE: Cardiodiabetes Update: A Textbook of Cardiology

Author

1. Panikar Vijay
2. Vadgama Jimit
3. Kamat Tejas

ISBN

9789352703043

DOI

10.5005/jp/books/14130_64

Edition

1/e

Publishing Year

2018

Pages

Author Affiliations

1. KG Somaiya Medical College, Mumbai, Maharashtra, India, KJ Somiaya Medical college; Lilavati Hospital, Mumbai, Maharashtra, India, Mumbai, Maharashtra, India, Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India, Lilavati Hospital, Mumbai, Maharashtra, India, Lilavati Hospital, Mumbai, India
2. Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India, Thyroid and Hormone Clinic, Surat, Gujarat, India, Swaminarayan Diabetes, Thyroid and Hormone Clinic, Surat, Gujarat, India
3. Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India, Lilavati Hospital, Mumbai, Maharashtra, India, Diabetes Care, Panaji, Goa, India

Chapter keywords

Lixisenatide, dipeptidyl peptidase-4, DPP4, acute coronary syndrome, ACS, type 2 diabetes mellitus, T2DM, glucagon-like peptide-1 receptor agonist, GLP-1RA, cardiovascular, CV

Abstract

Abstract

Lixisenatide is a synthetic glucagon-like peptide-1 receptor agonist (GLP-1RA) with a plasma half-life of 1.5–4.5 hours. It is a potent and selective GLP-1RA action and is more resistant to proteolysis by dipeptidyl peptidase-4 (DPP4) than native GLP-1 with a binding affinity that is approximately 4 times greater than human GLP-1 hormone. These factors collectively enable once-a-day dosing of lixisenatide. Evaluation of Lixisenatide in Acute Coronary Syndrome (ELIXA) was a randomized, double-blind, placebo controlled, parallel-group, and multicenter phase III event driven trial that assessed the effects of lixisenatide added to standard T2DM therapy on cardiovascular (CV) morbidity and mortality in patients with a recent acute coronary syndrome (ACS).

Related Books

Manual of Essential Hypertension

Nihar Mehta
MCQs in Cardiology for DM Entrance Examination

Vinod Sharma
Decision Making in Cardiology: An Algorithmic Approach

Achyut Sarkar
IAP Specialty Series on Pediatric Cardiology

R Krishna Kumar, Shakuntala S Prabhu, M Zulfikar Ahamed, Shreepal Jain
Manual of Echocardiography

Navin C Nanda, Gültekin Karakuş, Aleks Değirmencioğlu
Golwalla’s Electrocardiography for Medical Students and General Practitioners

Sharukh A Golwalla
Bedside Cardiology

Achyut Sarkar
CSI Cardiology Update 2022 (2 Volumes)

Vijay Bang, Ashish Deshpande, Vigyan Bang
ECG in Medical Practice

ABM Abdullah
Textbook of Interventional Cardiology

Samir Kapadia, Derek Chew, Fernando Cura, Philippe L L’Allier, Marco Roffi, E Murat Tuzcu