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Chapter-20 Guidelines for Fluid Resuscitation in Trauma Patients

BOOK TITLE: Practice Guidelines in Anesthesia-2

Author
1. Arora Deep
2. Pahwa Deepak
ISBN
9789352703067
DOI
10.5005/jp/books/14207_21
Edition
1/e
Publishing Year
2018
Pages
11
Author Affiliations
1. Medanta—The Medicity, Gurugram, Haryana, India, Max Smart Hospital, New Delhi, India
2. Medanta—The Medicity, Gurugram, Haryana, India
Chapter keywords
Fluid resuscitation, trauma, trauma induced coagulopathy, TIC, hypoperfusion, thrombomodulin, fluid therapy, blood product

Abstract

This chapter describes guidelines for fluid resuscitation in trauma patients. Trauma is a major cause of morbidity and mortality all over the world. Trauma induced coagulopathy (TIC) is an endogenous hypocoagulable state that occurs in the setting of tissue hypoperfusion and is primarily mediated by activation of protein C. Severe injury accompanied by tissue hypoperfusion leads to increased endothelial and circulating thrombomodulin, which subsequently binds thrombin. Severe injury accompanied by tissue hypoperfusion leads to increased endothelial and circulating thrombomodulin, which subsequently binds thrombin. This chapter covers the pathophysiology, recommendations, damage control resuscitation, assessment of the patient on arrival, fluid therapy, blood products, special situations, turning off massive transfusion, adjuncts to fluid therapy, and future trends.

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