The term \"Mood stabilizers\" was first introduced in reference to lithium salts when it was found effective not only to alleviate mania but also prevented both manic and depressive episodes. Now various drugs including some anti-epileptics and second generation anti-psychotics have been found to be effective in bipolar mood disorders. Mood stabilizer includes lithium carbonate, sodium valproate, carbamazepine, lamotrigine, and atypical antipsychotics. Combination of atypical antipsychotics with valproate or lithium has been found to be very effective in acute phases as well as for maintenance therapy. Anticonvulsants like gabapentin, oxacarbazepine, topiramate and tiagabine have also been found to be useful.