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Chapter-10 Non-Hodgkin Lymphomas, Plasma Cell Neoplasms and Histiocytic/Dendritic Cell Neoplasm

BOOK TITLE: Hematopathology Pearls

Author
1. Zhang Da
ISBN
9789352703234
DOI
10.5005/jp/books/14222_11
Edition
2/e
Publishing Year
2018
Pages
72
Author Affiliations
1. The University of Kansas School of Medicine, Kansas City, Kansas, USA, University of Kansas Medical Center, Kansas City, Kansas, USA, University of Kansas Medical Center, Kansas City, Kansas 66160, USA, University of Kansas Medical Center Kansas City, Kansas 66160, USA
Chapter keywords
Non-Hodgkin lymphoma, plasma cell neoplasm, juvenile xanthogranuloma, JXG, Erdheim-Chester disease, follicular lymphoma, FL, mantle cell lymphoma, MCL, Burkitt lymphoma, BL, plasma cell disorder, osteosclerotic myeloma

Abstract

This chapter discusses non-Hodgkin lymphomas, plasma cell neoplasms and histiocytic or dendritic cell neoplasm. Non-Hodgkin lymphomas are a heterogeneous group of malignancies. Their clinical presentation and course vary from indolent to aggressive. Indolent lymphomas are often disseminated at the time of diagnosis and frequently involve bone marrow. Over the last decade, significant progress has been made in the molecular characterizations of lymphomas, but the classification of lymphomas is still evolving. The prognosis of non-Hodgkin lymphomas depends on the type, the stage, and the cytogenetic and molecular features. This chapter covers the comparison of immunophenotype of small B-cell lymphomas, follicular lymphoma (FL), mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL), comparison of T-cell or histiocyte rich large B-cell lymphoma (THRLBCL) and nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), Burkitt lymphoma (BL), mature T-cell and natural killer (NK) cell neoplasm, angioimmunoblastic T-cell lymphoma (AITL), molecular and cytogenetic features of anaplastic large cell lymphoma (ALCL), plasma cell neoplasms, monoclonal immunoglobulin and plasma cell disorders, osteosclerotic myeloma (POEMS Syndrome), histiocytic and dendritic cell neoplasms, juvenile xanthogranuloma (JXG), and Erdheim-Chester disease.

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