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Chapter-14 Prophylactic Salpingectomy at Hysterectomy for Benign Diseases as an Effective Tool for Reducing Pelvic Serous Carcinoma: A Prospective Case Control Study

BOOK TITLE: Manual of Clinical Dilemma in Mature Women

Author
1. Kar Tushar
2. Kar Asaranti
3. Nayak Bhagyalaxmi
4. Dhal Ipsita
ISBN
9789352703739
DOI
10.5005/jp/books/18026_15
Edition
1/e
Publishing Year
2018
Pages
7
Author Affiliations
1. SCB Medical College, Cuttack, Orissa, India, Chairperson Oncology, FOGSI (2004-09), SCB Medical College, Cuttack, Veer Surendra Sai Institute of Medical Sciences and Research (VIMSAR), Sambalpur, Odisha, India, Srusti Hospital and Acharya Harihar Regional Cancer Centre (AHRCC), Cuttack, Odisha, India, Lady Hardinge Medical College, New Delhi, India
2. SCB Medical College and Hospital Joint Secretary (HQ) IAPM, OJPM, Cuttack, Orissa, India, SCB Medical College, Cuttack, Orissa, Srusti Hospital and Acharya Harihar Regional Cancer Centre (AHRCC), Cuttack, Odisha, India, Lady Hardinge Medical College, New Delhi, India
3. Acharya Harihar Regional Cancer Center, Cuttack, Acharya Harihar Regional, Cancer Center, Cuttack, Odisha, India, Acharya Harihar Regional Cancer Center, Cuttack, Odisha, India, Srusti Hospital and Acharya Harihar Regional Cancer Centre (AHRCC), Cuttack, Odisha, India, Lady Hardinge Medical College, New Delhi, India
4. Srusti Hospital and Acharya Harihar Regional Cancer Centre (AHRCC), Cuttack, Odisha, India, Lady Hardinge Medical College, New Delhi, India
Chapter keywords
High-grade serous carcinoma, HGSC, ovarian carcinoma, OC, tubal carcinoma, TC, primary peritoneal carcinoma, PPC, fallopian tube, salpingectomy

Abstract

Pelvic high-grade serous carcinomas (HGSCs), including ovarian carcinoma (OC), tubal carcinoma (TC), and primary peritoneal carcinomas (PPC), receive much attention from clinicians and researchers because of their usually advanced stage at presentation, rapid progression, extraovarian disease at the time of diagnosis, poor prognosis and high fatality rate. Lack of a proper screening method in these cases is the cause of their late detection. Recently, the distal fallopian tube has been documented as a common (80%) site of tumor origin in BRCA+ve (BRCA1 or BRCA2) women undergoing risk reducing salpingo-oophorectomy. Salpingectomy is a prophylactic or preventive surgery to remove the entire fallopian tubes with all hysterectomies for women at high risk of ovarian, tubal and peritoneal cancers.

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