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Chapter-09 Conventional and Liquid-based Cytology

BOOK TITLE: Manual of Clinical Dilemma in Mature Women

Author
1. Peedicayil Abraham
2. Manoj Ramani
ISBN
9789352703739
DOI
10.5005/jp/books/18026_10
Edition
1/e
Publishing Year
2018
Pages
8
Author Affiliations
1. Christian Medical College, Vellore, abraham@cmcvellore.ac.in, Christian Medical College, Vellore, India, Christian Medical College, Vellore, Tamil Nadu, India, Christian Medical College and Hospital, Vellore, Tamil Nadu, India
2. Christian Medical College and Hospital, Vellore, Tamilnadu, India
Chapter keywords
Conventional cytology, liquid-based cytology, LBC, Papanicolaou test, human papillomavirus, HPV, staining, squamous intraepithelial lesion, SIL

Abstract

In the last century, cervical cancer was the most common cause of cancer deaths in women worldwide and continues to be a significant burden in developing countries now. The Papanicolaou (Pap) test and organized screening brought about a remarkable decline in cervical cancer mortality in developed countries. This is the most successful cancer screening test, which has stood the test of time and continues to be a very good method. However, the scenario in India is different, as is in most developing countries. In spite of the high burden of cervical cancer, there is no structured screening program. Cytology is not available in many centers and it is mainly opportunistic screening that is being done. The quality of cytological services will depend on proper sample collection from the ectocervix and endocervix, proper smear preparation and staining by the cytotechnician, and proper reading and interpretation of the slide with supervision by a cytopathologist.

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