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Chapter-20 Peripartum Cardiomyopathy

BOOK TITLE: Manual of High-Risk Pregnancy

Author
1. Singh Anita
2. Shrivastava Aashita
ISBN
9789352703920
DOI
10.5005/jp/books/14143_21
Edition
1/e
Publishing Year
2018
Pages
6
Author Affiliations
1. Patna Medical College Hospital, Patna, Sir Ganga Ram Hospital, New Delhi, India, Patna Medical College, Patna, Bihar, India; Endocrinology Committee, FOGSI, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, Jyoti Punj Hospital and Jan Chikitsa Hospital, Patna; Patna Medical College and Hospital, Patna, Bihar, India; FOGSI (EZ), 2020; Endocrinology Committee, FOGSI, 2014–2016; IFS, Bihar Chapter, Jyoti Punj Hospital and Jan Chikitsa, Hospital, Patna; Patna Medical College and Hospital, Patna, Bihar, India
2. Nalanda Medical College and Hospital, Patna, Bihar, India, Nishant Hospital, Patna, Bihar, India
Chapter keywords
Peripartum cardiomyopathy, PPCM, breastfeeding, inflammation, myocarditis, abnormal immunologic, pharmacologic therapy, hemodynamic response, prolactin, genetic factor

Abstract

Peripartum cardiomyopathy (PPCM) is a rare but critical disorder causing heart failure in women in late pregnancy or puerperium. European Society of Cardiology (ESC) working group on PPCM defines PPCM as “an idiopathic cardiomyopathy presenting with heart failure secondary to left ventricle systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause of heart failure is found”. This chapter covers the epidemiology of PPCM, etiology of PPCM, inflammation, myocarditis, abnormal immunologic and hemodynamic responses to pregnancy, prolactin, genetic factors, diagnosis, and breastfeeding. Breastfeeding is strongly discouraged in more symptomatic patients as pharmacologic therapy to the patient can be passed on to the child. If breastfeeding is considered in these women, it has to be with careful monitoring of the baby.

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