The objective of this chapter is to introduce the placenta accreta. These abnormalities of placental insertion are serious as there are occurs trophoblastic invasion into the myometrium to a variable extent. Bleeding from these sites can be dangerous. Placenta accreta is becoming more important to obstetricians as the number of cesarean sections is on rise. This chapter covers the development of human placenta, placenta accreta, diagnosis, and management. Human placenta is hemochorial, as the maternal blood directly bathes the syncytiotrophoblast. Placenta accreta is a condition in which all or part of the placenta is adherent to the uterine wall because of myometrial invasion by chorionic villi. It may occur when there is a primary deficiency or secondary damage to deciduas basalis and Nitabuch’s layer.