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Chapter-03 Pathophysiologic Changes in Diabetic Pregnancy

BOOK TITLE: Clinical Guidelines for Management of Diabetes in Pregnancy

Author
1. Garg Sandeep
2. Dhar Jahnvi
ISBN
9789352703951
DOI
10.5005/jp/books/18049_4
Edition
1/e
Publishing Year
2018
Pages
7
Author Affiliations
1. Maulana Azad Medical College, New Delhi, India
2. Maulana Azad Medical College, New Delhi, India
Chapter keywords
Pathophysiologic change, diabetic pregnancy, diabetic mellitus, DM, metabolic disorder, gestational diabetes mellitus, GDM, dyslipidemia, thyroid dysfunction, insulin resistance, hormonal imbalance

Abstract

This chapter focuses on pathophysiologic changes in diabetic pregnancy. Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which high blood sugar levels prevail over a prolonged period of time. It is due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced. Gestational diabetes mellitus encompasses various pathophysiological alterations which can have a profound impact on the pregnancy course with an adverse effect on the mother and the child. Various physiological alterations include hypertension (systolic and diastolic blood pressure), dyslipidemia, thyroid dysfunction, insulin resistance (with/out metabolic syndrome), increase in waist, hormonal imbalances, and fetal outcome.

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