This chapter deals with the discussion on pediatric stoma care. Infants have different abdominal dimensions and musculature. The abdominal wall is very thin and the muscles give poor support for the stomas making prolapse much more common. It is difficult to site the stoma as ideally as an adult with regard to the umbilicus and pelvic bones. One should know that in children the stoma must be placed within the operative wound as opposed to a separate incision due to lack of space. Hence the pediatric stomas are much more difficult to look after, because all care is done by the child’s carers and the stomas are more difficult to fit and keep on. Conditions that necessitate a stoma are imperforate anus, Hirschsprung’s disease, inflammatory bowel disease, neonatal necrotising enterocolitis, spina bifida, accident injury, and meconium ileus. Specific aspect of pediatric stoma care has been also defined in this chapter.