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Chapter-57 Recurrent Implantation Failure

BOOK TITLE: Principles and Practice of Assisted Reproductive Technology

Author
1. PS Divyashree
ISBN
9789352705030
DOI
10.5005/jp/books/18020_58
Edition
2/e
Publishing Year
2019
Pages
26
Author Affiliations
1. Milann—The Fertility Center (A Unit of BACC Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann - The Fertility Center, Bengaluru, Karnataka, India, Milann—The Fertility Center, Bengaluru, Karnataka, India, Milann JP Nagar, Bengaluru, Karnataka, India, Genea Fertility Center, Bengaluru, Karnataka, India, Genia Fertility Center, Bengaluru, Karnataka, India
Chapter keywords
Recurrent implantation failure, thin endometrium, endometrial microbiota, gamete, sperm DNA damage, endometrial receptivity, oocyte quality, DNA fragmentation index, embryo transfer, zygote intra-fallopian transfer

Abstract

Failure of implantation is a consequence of embryo and/or uterine factors. The exact mechanism of implantation is far from clearly understood. Recurrent implantation failure (RIF) refers to failure to achieve a clinical pregnancy after transfer of at least four good-quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years. RIF is a frustrating event for both patients and their clinicians. The aim of this chapter is to condense the reported etiologies for RIF, focus on the suggested investigations to be implemented, and analyze the suggested treatment strategies.

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