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Chapter-58 Empty Follicle Syndrome

BOOK TITLE: Principles and Practice of Assisted Reproductive Technology

Author
1. Rao Kamini A
2. Davuluri Sindhuma
ISBN
9789352705030
DOI
10.5005/jp/books/18020_59
Edition
2/e
Publishing Year
2019
Pages
6
Author Affiliations
1. Bangalore Assisted Conception Centre, Bangalore, Milann Fertility Centre, Bangaluru, Karnataka, India, Milann—The Fertility Center, Bengaluru, Karnataka, India, Milann (A Unit of BACC Health care Private Limited), Bengaluru, Karnataka, India, Milann (A Unit of BACC Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann (A Unit of BACC, Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann Group of Fertility Centers, Bengaluru, Karnataka, India, Bengaluru, Karnataka, India, Bengaluru, Milann—The Fertility Center (A Unit of BACC Healthcare Pvt Ltd), Bengaluru, Karnataka, India, Milann—The Fertility Center (A Unit of BACC Health Care Pvt Ltd), Bengaluru, Karnataka, India, Bangalore Assisted Conception Centre, Bangalore, Karnataka, India, BACC Health Care Private Limited, Bengaluru, Karnataka, India, Bangalore Assisted Conception Center (BACC), Bengaluru, Karnataka, India, FOGSI-2001; Bangalore Assisted Conception Center (An ISO 9002 Organization), Karnataka, India, Bangalore Assisted Conception Center
2. Milann—The Fertility Center, Bengaluru, Karnataka, India
Chapter keywords
Empty follicle syndrome, in vitro fertilization, hCG trigger, gonadotropin-releasing hormone trigger, follicle-stimulating hormone, luteinizing hormone, absent LH surge

Abstract

This chapter seeks to familiarize the readers with empty follicle syndrome (EFS). Empty follicle syndrome is a condition where no oocytes are retrieved despite repeated aspiration and flushing, after an apparently adequate ovarian response to stimulation, evidenced by serial ultrasound and adequate steroidogenesis. Due to uncertainty of its existence and variability in the inclusion criteria across different studies, its prevalence varies over a wide range, from as low as 0.045% to 7% of in vitro fertilization (IVF) cycles. Risk factors for early follicle syndrome, diagnosis and prevention of EFS, management of EFS in the current cycle, and management of subsequent cycles after EFS are the important topics which are covered throughout this chapter.

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