Recurrent pregnancy loss (RPL) has been redefined as two or more clinical pregnancy losses, which are not necessarily consecutive. A couple with RPL needs evaluation with the right tools and management with appropriate interventions. These interventions could be as minimal as tender loving care (TLC) and as complex as involving genetic workup with preimplantation genetic screening (PGS) or use of therapeutic agents altering immunologic mechanisms of RPL. Although more than half of these patients conceive on their own in due course of time, these interventions are required to minimize time lag and ensure successful outcomes. Over vigorous workup draining the couple financially, on a superseded emotional turmoil, triggers anxiety, and apprehension. Avoidance of blanket therapy with judicious use of the available parameters and evidence-based approach is warranted. Optimization of complex clinical situations into pleasant pregnancy with definitive end points of “healthy mother and a healthy baby” becomes a reality for these couples sailing through troubled waters.