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Chapter-03 Preclinical In Vitro Screening Methods to Predict Drug Safety during Drug Development Process

BOOK TITLE: Drug Discovery and Clinical Research

Author
1. Senthilkumari Srinivasan
ISBN
9789352705771
DOI
10.5005/jp/books/18166_4
Edition
2/e
Publishing Year
2019
Pages
5
Author Affiliations
1. Aravind Medical Research Foundation (AMRF), #1, Anna Nagar, Madurai (Tamil Nadu), India, Aravind Medical Research Foundation (AMRF), Madurai, Tamil Nadu, India
Chapter keywords
Drug safety, clinical trials, cytotoxicity screening, membrane integrity, lactate dehydrogenase, LDH, cellular metabolite content, mitochondrial function, lysosomal function, apoptosis, toxicological evaluation

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