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Chapter-208 Dupuytren's Contractures

BOOK TITLE: Textbook of Orthopedics & Trauma (4 Volumes)

Author
1. Gouk Conor JC
2. Bindra Randy R
ISBN
9789385891052
DOI
10.5005/jp/books/12869_209
Edition
3/e
Publishing Year
2016
Pages
7
Author Affiliations
1. Royal Devon and Exeter Hospital, Exeter EX2, SOW, UK
2. Griffith University and Gold Coast University Hospital, Southport, Australia
Chapter keywords
Dupuytren’s disease, Dupuytren’s contracture, extracellular matrix, ECM, palmar fascia, proximal interphalangeal joint, PIPJ, distal interphalangeal joint, DIPJ

Abstract

Dupuytren’s disease is a fibromatous disease affecting the palmar and digital fascia. It leads to progressive contracture and flexion of the affected digit, or digits, at the metacarpophalangeal joint (MCPJ) and the interphalangeal joints (IPJs). Other fibromatoses include Peyronie’s disease (penile) and Ledderhose disease. Dupuytren’s disease, often referred to as “Viking’s disease”, has a strong genetic component, and is associated with alcoholism and diabetes mellitus. The objective of this chapter is to cover a broad discussion on epidemiology, pathophysiology, anatomy, clinical presentation, disease classification and treatment of Dupuytren’s disease.

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