This chapter discusses tuberculosis of the elbow joint. Tuberculous disease of the elbow constitutes nearly 2–5% of all cases of skeletal tuberculosis. The disease commonly starts from the olecranon or the lower end of humerus, sometimes the onset is synovial or from the upper end of radius. In developing countries, the diagnosis can be readily made on clinicoradiological bases. In early stage of disease, the clinicoradiological features resemble any inflammatory condition. This chapter also discusses the clinical feature, differential diagnosis, and operative treatment. Excision arthroplasty is justified after the completion of growth potential when the disease has healed with the elbow in unacceptable position, or in a case of advanced arthritis and gross ankylosis where one is impelled to obtain a mobile joint.